Mental, neurological, and substance use disorders and related disabilities (MNS disorders) are leading contributors to the burden of disease globally. (The term MNS is a relatively new acronym coined by the World Health Organization [WHO] to refer to the complete range of disorders of the brain and the mind for its mental health Gap Action Programme [mhGAP].) Unipolar depressive disorders, alcohol use disorders, and self-inflicted injuries rank within the top 20 leading causes of burden of disease (as measured by disability adjusted life years [DALYs]) across all age groups and neuropsychiatric disorders, collectively, account for 22% of DALYs for women aged 15–59 years . Even in the least developed regions of the world where infectious and parasitic diseases are prominent, MNS disorders are a major source of DALYs lost . Over the next 20 years, it is estimated that neuropsychiatric disorders alone will account for the loss of an additional US$16.1 trillion with “dramatic impacts on productivity and quality of life” . Suicide claims the lives of at least 1 million people annually  with over 85% of suicides occurring in low- and middle-income countries (LMICs). Nearly 4% of all deaths globally are attributable to alcohol . While many MNS disorders begin in childhood and adolescence (when an individual is being educated, establishing effective social relationships, and preparing for work), the burden associated with dementia and stroke is expected to accelerate with increasing life expectancies around the world. Currently, it is estimated that about 25 million people have dementia; this number is expected too reach over 80 million by 2040, with nearly three-quarters of affected people living in LMICs .